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Ninlaro and Hepatic impairment

Result of checking the interaction of drug Ninlaro and disease Hepatic impairment for safety when used together.

Check result:
Ninlaro <> Hepatic impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pharmacokinetic studies of ixazomib in patients with moderate to severe hepatic impairment, showed an increase AUC when compared to patients with normal hepatic function. The pharmacokinetic of ixazomib was similar in patients with normal hepatic function and in patients with mild hepatic impairment. It is recommended to reduce the starting dose in patients with moderate to severe hepatic impairment. Caution should be exercised when ixazomib is administered to patients with moderate to severe hepatic function and monitoring of liver function tests is recommended as appropriate.

Ninlaro

Generic Name: ixazomib

Brand Name: Ninlaro

Synonyms: n.a.

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