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Netarsudil and Latanoprost and Renal/liver disease

Result of checking the interaction of drug Netarsudil and Latanoprost and disease Renal/liver disease for safety when used together.

Check result:

Netarsudil and Latanoprost <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Prostaglandin F2-alpha analogues are hydrolyzed by esterases in the cornea to their corresponding active free acid form, which is absorbed systemically and metabolized by the liver via fatty acid beta-oxidation, then eliminated by the kidney. These agents have not been adequately studied in the treatment of patients with impaired renal and/or hepatic function. Therapy with ophthalmic prostaglandin F2-alpha analogues should be administered cautiously in such patients.

References:

"Product Information. Xalatan (latanoprost ophthalmic)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Travatan (travoprost ophthalmic)" Alcon Laboratories Inc, Fort Worth, TX.

Netarsudil and Latanoprost

Generic Name: latanoprost / netarsudil ophthalmic

Brand Name: Rocklatan

Synonyms: Latanoprost and netarsudil ophthalmic

What is Netarsudil and Latanoprost?