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Neomycin, Polymyxin B, and Hydrocortisone Otic Suspension and Perforated tympanic membrane

Result of checking the interaction of drug Neomycin, Polymyxin B, and Hydrocortisone Otic Suspension and disease Perforated tympanic membrane for safety when used together.

Check result:
Neomycin, Polymyxin B, and Hydrocortisone Otic Suspension <> Perforated tympanic membrane
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Like other aminoglycosides, neomycin is potentially ototoxic, both to vestibular and to auditory functions. Therapy with neomycin otic preparations should be administered cautiously in patients with chronic otitis media or a perforated tympanic membrane. The risk of ototoxicity may be increased if medication enters the middle ear.

References:
  • "Product Information. Mycifradin (neomycin)." Emerson Laboratories, Texarkana, TX.
Neomycin, Polymyxin B, and Hydrocortisone Otic Suspension

Generic Name: hydrocortisone / neomycin / polymyxin b otic

Brand Name: Cortisporin Otic, Drotic, Masporin Otic, Cortomycin, Otocort Sterile Solution, Cortatrigen Modified, Otimar, Pediotic, AK-Spore HC Otic Suspension, Otocort Sterile Suspension, UAD Otic, Cortatrigen, Antibiotic Ear, Cort-Biotic, Oti-Sone, AK-Spore HC, Casporyn HC

Synonyms: Hydrocortisone, neomycin, and polymyxin B otic, Neomycin, Polymyxin B, and Hydrocortisone (Otic)

Neomycin, Polymyxin B, and Hydrocortisone Otic Suspension <> Perforated tympanic membrane
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of medications that are intended for the treatment of otitis externa or other conditions of the external ear canal should generally be avoided, or otherwise approached with caution, in patients with a perforated tympanic membrane due to the risk of toxicity from medication that may get into the middle ear. Caution is also advised in patients with longstanding, chronic otitis media because of the possibility of a perforated tympanic membrane in such patients.

References:
  • "Multum Information Services, Inc. Expert Review Panel"
  • Behrman R, Kliegman R, Arvin A, Nelson W, eds. "Nelson Textbook of Pediatrics. 15th ed." Philadelphia, PA: W.B. Saunders Company (1996):
Neomycin, Polymyxin B, and Hydrocortisone Otic Suspension

Generic Name: hydrocortisone / neomycin / polymyxin b otic

Brand Name: Cortisporin Otic, Drotic, Masporin Otic, Cortomycin, Otocort Sterile Solution, Cortatrigen Modified, Otimar, Pediotic, AK-Spore HC Otic Suspension, Otocort Sterile Suspension, UAD Otic, Cortatrigen, Antibiotic Ear, Cort-Biotic, Oti-Sone, AK-Spore HC, Casporyn HC

Synonyms: Hydrocortisone, neomycin, and polymyxin B otic, Neomycin, Polymyxin B, and Hydrocortisone (Otic)