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Neomycin, polymyxin b, and hydrocortisone Otic and Burns

Result of checking the interaction of drug Neomycin, polymyxin b, and hydrocortisone Otic and disease Burns for safety when used together.

Check result:
Neomycin, polymyxin b, and hydrocortisone Otic <> Burns
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Topical aminoglycosides should not be used on serious burns. When applied locally, aminoglycosides are generally not absorbed to a significant extent through intact skin but readily absorbed through denuded, burned, or granulating skin. Systemic adverse effects of aminoglycosides include nephrotoxicity and ototoxicity to vestibular and auditory functions. In general, topical aminoglycosides should not be used on large areas of the body or for more than 7 days without medical supervision.

References:
  • "Product Information. Myciguent (neomycin topical)." Pharmacia and Upjohn, Kalamazoo, MI.
Neomycin, polymyxin b, and hydrocortisone Otic

Generic Name: hydrocortisone / neomycin / polymyxin b otic

Brand Name: Cortisporin Otic, Drotic, Masporin Otic, Cortomycin, Otocort Sterile Solution, Cortatrigen Modified, Otimar, Pediotic, AK-Spore HC Otic Suspension, Otocort Sterile Suspension, UAD Otic, Cortatrigen, Antibiotic Ear, Cort-Biotic, Oti-Sone, AK-Spore HC, Casporyn HC

Synonyms: Hydrocortisone, neomycin, and polymyxin B otic, Neomycin, Polymyxin B, and Hydrocortisone (Otic)