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Myochrysine and Bone marrow aplasia

Result of checking the interaction of drug Myochrysine and disease Bone marrow aplasia for safety when used together.

Check result:

Myochrysine <> Bone marrow aplasia

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of auranofin and other gold compounds is contraindicated in patients with a history of gold- induced bone marrow aplasia. Prior to gold compounds therapy, a complete blood count with a differential, platelet count, urinalysis, and renal and liver function tests should be performed. A complete blood count with a differential, platelet count, and urinalysis should be done at least monthly during therapy. Hematological warning signs of gold toxicity include a drop in hemoglobin, leukopenia (WBC < 4,000/mm3), granulocytopenia (< 1,500/mm3), and thrombocytopenia (<100,000/mm3).

References:

"Product Information. Ridaura (auranofin)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Solganal (aurothioglucose)." Schering Laboratories, Kenilworth, NJ.
"Product Information. Myochrysine (gold sodium thiomaleate)." Merck & Co, Inc, West Point, PA.

Myochrysine

Generic Name: gold sodium thiomalate

Brand Name:

Synonyms: n.a.

What is Myochrysine?