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Micafungin and Hepatotoxicity

Result of checking the interaction of drug Micafungin and disease Hepatotoxicity for safety when used together.

Check result:
Micafungin <> Hepatotoxicity
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Laboratory abnormalities in liver function tests have been observed in healthy volunteers and patients treated with echinocandins, and clinical hepatic abnormalities have occurred in some patients with serious underlying conditions who were receiving multiple concomitant medications with echinocandin therapy. Isolated cases of significant hepatic dysfunction, hepatitis, or worsening hepatic failure have also been reported, although a causal relationship has not been established. Therapy with echinocandins should be administered cautiously in patients with preexisting liver disease. Liver function should be monitored regularly during therapy.

References:
  • "Product Information. Mycamine (micafungin)." Fujisawa, Deerfield, IL.
  • "Product Information. Eraxis (anidulafungin)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
  • "Product Information. Cancidas (caspofungin)" Merck & Co, Inc, West Point, PA.
Micafungin

Generic Name: micafungin

Brand Name: Mycamine

Synonyms: n.a.

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