Drug search by name

Methoxsalen (Systemic) and Previous x-ray therapy

Result of checking the interaction of drug Methoxsalen (Systemic) and disease Previous x-ray therapy for safety when used together.

Check result:

Methoxsalen (Systemic) <> Previous x-ray therapy

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

PUVA (psoralen and UVA photochemotherapy) may be associated with increased risks of squamous cell carcinoma, basal cell carcinoma and melanoma. Methoxsalen, a psoralen, markedly enhances skin reactivity to UVA radiation, and exposure to sunlight and/or UVA can cause premature aging of the skin and skin cancer. The total lifetime dose of UVA that can be safely administered has not been established. Therefore, PUVA should be given cautiously in patients with a history of x-ray or grenz ray therapy. Close monitoring for signs of carcinoma is recommended. The usual restrictions concerning sun exposure before and after treatment as well as prescribed dosage must be followed closely.

References:

"Product Information. Oxsoralen Lotion (methoxsalen topical)." ICN Pharmaceuticals, Costa Mesa, CA.
"Product Information. Oxsoralen (methoxsalen)." ICN Pharmaceuticals Inc, Costa Mesa, CA.

Methoxsalen (Systemic)

Generic Name: methoxsalen

Brand Name: 8-Mop, Oxsoralen-Ultra, Uvadex

Synonyms: Methoxsalen

What is Methoxsalen (Systemic)?