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Amphocin and Anemia

Result of checking the interaction of drug Amphocin and disease Anemia for safety when used together.

Check result:
Amphocin <> Anemia
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Intravenous amphotericin B therapy may depress erythropoietin and red blood cell production and commonly causes a normocytic, normochromic anemia. Although the anemia is well tolerated by most patients and usually reverses completely within several months of stopping therapy, it may be problematic in patients with preexisting anemia. Intravenous therapy with amphotericin B should be administered cautiously in anemic patients or those predisposed to anemia. Frequent monitoring of blood counts and hemoglobin concentrations are recommended.

References:
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  • Miller R, Bates J "Amphotericin B toxicity." Ann Intern Med 71 (1969): 1089-95
  • "Amphotericin." Med Lett Drugs Ther 30 (1988): 30-2
  • Struijk D, Krediet R, Boeschoten E, Rietra JG, Arisz L "Antifungal treatment of candida peritonitis in continuous ambulatory peritoneal dialysis patients." Am J Kidney Dis 9 (1987): 66-70
  • "Product Information. Fungizone (amphotericin B)." Bristol-Myers Squibb, Princeton, NJ.
  • Maddux M, Barriere S "A review of complications of amphotericin B therapy: recommendations for prevention and management." Drug Intell Clin Pharm 14 (1980): 177-81
  • American Medical Association, Division of Drugs and Toxicology "Drug evaluations annual 1994." Chicago, IL: American Medical Association; (1994):
Amphocin

Generic Name: amphotericin b

Brand Name: Fungizone, Fungizone For Tissue Culture, Amphocin

Synonyms: n.a.

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