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Mesnex Oral and Autoimmune disorders

Result of checking the interaction of drug Mesnex Oral and disease Autoimmune disorders for safety when used together.

Check result:
Mesnex Oral <> Autoimmune disorders
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Mesna is a thiol (SH) compound. Hypersensitivity reactions including anaphylaxis have occurred in patients with autoimmune disorders, the majority of whom received high dosages of mesna orally. Therapy with mesna should be administered cautiously in patients with autoimmune disorders.

References:
  • Reinhold-Keller E, Mohr J, Christophers E, Nordmann K, Gross WL "Mesna side effects which imitate vasculitis." Clin Investig 70 (1992): 698-704
  • Seidel A, Andrassy K, Ritz E, Kasser U, Lemmel EM "Allergic reactions to mesna." Lancet 338 (1991): 381
  • Lang E, Goos M "Hypersensitivity to mesna." Lancet 2 (1985): 329
  • Zonzits E, Aberer W, Tappeiner G "Drug eruptions from mesna. After cyclophosphamide treatment of patients with systemic lupus erythematosus and dermatomyositis." Arch Dermatol 128 (1992): 80-2
  • "Product Information. Mesnex (mesna)." Bristol-Myers Squibb, Princeton, NJ.
Mesnex Oral

Generic Name: mesna

Brand Name: Mesnex

Synonyms: Mesnex (oral/injection), Mesnex

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