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Mekinist and GI perforation
Result of checking the interaction of drug Mekinist and disease GI perforation for safety when used together.
Check result:
Mekinist <> GI perforation
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Colitis and gastrointestinal perforation, sometimes with fatal outcomes can occur with the use of trametinib. Care and close monitoring is recommended with using this agent in patients with gastrointestinal complications. Monitor patients closely for colitis and gastrointestinal perforations.
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