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Megace ES and Diabetes mellitus

Result of checking the interaction of drug Megace ES and disease Diabetes mellitus for safety when used together.

Check result:

Megace ES <> Diabetes mellitus

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Megestrol, like other progestational agents, can cause glucose intolerance. In addition, it may have glucocorticoid activity. New onset diabetes and exacerbation of preexisting diabetes have been reported in association with the chronic use of megestrol. Patients with diabetes mellitus should be monitored more closely during therapy with megestrol, and adjustments made accordingly in their antidiabetic regimen.

References:

Hardy H, Esch LD, Morse GD "Glucose disorders associated with HIV and its drug therapy." Ann Pharmacother 35 (2001): 343-51
Leinung MC, Liporace R, Miller CH "Induction of adrenal suppression by megestrol acetate in patients with AIDS." Ann Intern Med 122 (1995): 843-5
Henry K, Rathgaber S, Sullivan C, McCabe K "Diabetes mellitus induced by megestrol acetate in a patient with AIDS and cachexia." Ann Intern Med 116 (1992): 53-4
Kilby JM, Tabereaux PB "Severe hyperglycemia in an HIV clinic: preexisting versus drug- associated diabetes mellitus." J Acquir Immune Defic Syndr Hum Retrovirol 17 (1998): 46-50
"Product Information. Megace (megestrol)." Bristol-Myers Squibb, Princeton, NJ.

Megace ES

Generic Name: megestrol

Brand Name: Megace ES, Megace

Synonyms: n.a.

What is Megace ES?