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Lumacaftor and ivacaftor and Renal impairment

Result of checking the interaction of drug Lumacaftor and ivacaftor and disease Renal impairment for safety when used together.

Check result:

Lumacaftor and ivacaftor <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Ivacaftor has not been studied in patients with renal impairment. No dose adjustment is necessary for patients with mild or moderate renal impairment, however, caution is recommended in patients with severe renal impairment or end-stage renal disease.

Lumacaftor and ivacaftor

Generic Name: ivacaftor / lumacaftor

Brand Name: Orkambi

Synonyms: Ivacaftor and lumacaftor, Lumacaftor and Ivacaftor

What is Lumacaftor and ivacaftor?