Lonsurf and Renal dysfunction
Result of checking the interaction of drug Lonsurf and disease Renal dysfunction for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:No adjustment to the starting dosage of products containing the combination ingredients, trifluridine and tipiracil is recommended for patients with mild or moderate renal impairment. The estimated mean AUC of trifluridine at steady state was 31% higher in patients with mild renal impairment and 43% higher in patients with moderate renal impairment than that in patient with normal renal function. The estimated mean AUC of tipiracil was 34% higher in patients with mild renal impairment and 65% higher in patients with moderate renal impairment than that in patients with normal renal function. Caution is recommended when using these agents in patient with severe renal impairment or end-stage renal disease as their pharmacokinetics have not been studied in these patients.
Lonsurf - Niewydolność nerek 
Lonsurf - disfunção renal 
Lonsurf - disfungsi buah pinggang 
Lonsurf - disfungsi ginjal 
Lonsurf - disfunzione renale 
Lonsurf - dysfonctionnement rénal 
Lonsurf - Nierenfunktionsstörung 
Lonsurf - disfuncion renal 
Lonsurf - почечная дисфункция 
Lonsurf - Böbrek yetmezliği 
Lonsurf - الفشل الكلوي 
Lonsurf - 肾功能不全