Drug search by name

Lidocaine and Hydrocortisone Cream and Renal dysfunction

Result of checking the interaction of drug Lidocaine and Hydrocortisone Cream and disease Renal dysfunction for safety when used together.

Check result:

Lidocaine and Hydrocortisone Cream <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Lidocaine topical is absorbed through intact skin and mucosal membranes. Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of lidocaine. Lidocaine is primarily eliminated by the kidney. Less than 10% is eliminated unchanged in the urine. Two active metabolites (MEGX and GX) have been identified that exhibit antiarrhythmic and convulsant properties. Serum concentrations of lidocaine and the active metabolites are increased and the half-life prolonged in patients with renal impairment. Therapy with lidocaine topical should be administered cautiously and dosing modified for repeated doses in patients with compromised renal function.

Lidocaine and Hydrocortisone Cream

Generic Name: hydrocortisone / lidocaine topical

Brand Name: Ana-Lex, LidaMantle HC, AnaMantle HC, Lidazone HC, AnaMantle HC Forte, Senatec HC, RectaGel HC, Peranex HC, LidaMantle HC Relief, Xyralid LP, Xyralid, BP Ana-Lex HC, LidoCort

Synonyms: Hydrocortisone and lidocaine (topical/rectal)

What is Lidocaine and Hydrocortisone Cream?