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Lidocaine and Epinephrine Injection and Sinus/AV node dysfunction

Result of checking the interaction of drug Lidocaine and Epinephrine Injection and disease Sinus/AV node dysfunction for safety when used together.

Check result:
Lidocaine and Epinephrine Injection <> Sinus/AV node dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of lidocaine is contraindicated in patients with Stokes-Adam syndrome, Wolff-Parkinson White syndrome, or second- or third-degree AV block in the absence of a functional artificial pacemaker, or congenital QT prolongation.

References:
  • Tagliente TM, Jayagopal S "Transient left bundle branch block following lidocaine." Anesth Analg 69 (1989): 545-7
  • Keidar S, Grenadier E, Palant A "Sinoatrial arrest due to lidocaine injection in sick sinus syndrome during amiodarone administration." Am Heart J 104 (1982): 1384-5
  • Hilleman DE, Mohiuddin SM, Destache CJ "Lidocaine-induced second-degree mobitz type II heart block." Drug Intell Clin Pharm 19 (1985): 669-73
  • "Product Information. Xylocaine (lidocaine)." Astra USA, Westborough, MA.
Lidocaine and Epinephrine Injection

Generic Name: epinephrine / lidocaine

Brand Name: D-Care 100X, Lignospan Forte, Lignospan Standard, Xylocaine MPF With Epinephrine, Xylocaine With Epinephrine

Synonyms: Lidocaine and Epinephrine

Interaction with food and lifestyle