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Leukine and Myeloid tumors

Result of checking the interaction of drug Leukine and disease Myeloid tumors for safety when used together.

Check result:

Leukine <> Myeloid tumors

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sargramostim primarily stimulates the proliferation of normal myeloid precursor cells but may also, theoretically, enhance tumor growth, particularly in myeloid malignancies. Therapy with sargramostim should be administered cautiously in patients with myeloid tumors. Additionally, if sargramostim is used for PBPC (peripheral blood progenitor cell) collection in such patients, tumor cells may be released from the marrow and collected in the leukapheresis product. The effect of reinfusion of tumor cells is uncertain at this time.

References:

"Product Information. Prokine (sargramostim)." Hoechst Marion-Roussel Inc, Kansas City, MO.
"Product Information. Leukine (sargramostim)." Immunex Corporation, Seattle, WA.

Leukine

Generic Name: sargramostim

Brand Name: Leukine

Synonyms: n.a.

What is Leukine?