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Leukine and Fluid retention

Result of checking the interaction of drug Leukine and disease Fluid retention for safety when used together.

Check result:

Leukine <> Fluid retention

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sargramostim may cause fluid retention. Edema, capillary leak syndrome, and pleural and/or pericardial effusion have been reported. Therapy with sargramostim should be administered cautiously in patients with preexisting fluid retention or congestive heart failure. Fluid retention caused or worsened by sargramostim is often reversible following discontinuation of therapy or reduction in dosage, with or without diuretic administration.

References:

"Product Information. Prokine (sargramostim)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Grant SM, Heel RC "Recombinant granulocyte-macrophage colony-stimulating factor (rGM- CSF). A review of its pharmacological properties and prospective role in the management of myelosuppression." Drugs 43 (1992): 516-60
"Product Information. Leukine (sargramostim)." Immunex Corporation, Seattle, WA.

Leukine

Generic Name: sargramostim

Brand Name: Leukine

Synonyms: n.a.

What is Leukine?