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Leucovorin Tablets and GI toxicity

Result of checking the interaction of drug Leucovorin Tablets and disease GI toxicity for safety when used together.

Check result:

Leucovorin Tablets <> GI toxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Leucovorin enhances the toxicity of 5-fluorouracil. When these drugs are administered concurrently in the palliative therapy of advanced colorectal cancer, gastrointestinal toxicities, particularly stomatitis and diarrhea are observed more commonly and may be more severe and of prolonged duration. Therapy with these agents must not be initiated or continued in patients who have symptoms of gastrointestinal toxicity of any severity until those symptoms have completely resolved. Monitor patients experiencing diarrhea and institute appropriate care.

Leucovorin Tablets

Generic Name: leucovorin

Brand Name: Wellcovorin

Synonyms: Leucovorin, Leucovorin Calcium

What is Leucovorin Tablets?