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Ledipasvir and sofosbuvir and Hepatic impairment

Result of checking the interaction of drug Ledipasvir and sofosbuvir and disease Hepatic impairment for safety when used together.

Check result:

Ledipasvir and sofosbuvir <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sofosbuvir is extensively metabolized in the liver. The safety and efficacy of sofosbuvir as a single agent have not been established in patients with decompensated cirrhosis. No dosage adjustment is required for patients with mild, moderate or severe hepatic impairment (Child-Pugh Class A, B or C).

Ledipasvir and sofosbuvir

Generic Name: ledipasvir / sofosbuvir

Brand Name: Harvoni

Synonyms: Ledipasvir and Sofosbuvir

What is Ledipasvir and sofosbuvir?