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Intron-A (Interferon Alfa-2b Injection Solution) and Hepatic dysfunction

Result of checking the interaction of drug Intron-A (Interferon Alfa-2b Injection Solution) and disease Hepatic dysfunction for safety when used together.

Check result:

Intron-A (Interferon Alfa-2b Injection Solution) <> Hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Dose-related increases in liver transaminase levels occur frequently during interferon-alfa therapy. Changes in LDH and alkaline phosphatase have been reported, primarily in patients with preexisting hepatic impairment. Patients with autoimmune hepatitis who have received interferon-alfa have experienced severe, life-threatening exacerbation of their disease. Therapy with interferon-alfa should be administered cautiously in patients with liver disease and should not be initiated in patients with autoimmune hepatitis.

References:

"Product Information. Intron A (interferon alfa-2b)." Schering Laboratories, Kenilworth, NJ.
"Product Information. Infergen (interferon alfacon-1)." Amgen, Thousand Oaks, CA.

Intron-A (Interferon Alfa-2b Injection Solution)

Generic Name: interferon alfa-2b

Brand Name: Intron A

Synonyms: Intron A

What is Intron-A (Interferon Alfa-2b Injection Solution)?