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Impavido and Sjogren-Larsson syndrome

Result of checking the interaction of drug Impavido and disease Sjogren-Larsson syndrome for safety when used together.

Check result:

Impavido <> Sjogren-Larsson syndrome

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of miltefosine is contraindicated in patients with Sjogren-Larsson syndrome. Miltefosine undergoes metabolic cleavage in hepatocytes to release choline. The fatty alcohol-containing fragment of miltefosine is then oxidized to palmitic acid, which enters the metabolism of fatty acids. However, this oxidation is blocked in patients with Sjogren-Larsson syndrome, who have a genetic defect in fatty aldehyde dehydrogenase activity.

Impavido

Generic Name: miltefosine

Brand Name: Impavido

Synonyms: n.a.

What is Impavido?